Computational Methods for Spatially Realistic Microphysiological Simulations

July 28 to August 1, 2008

Location: Pittsburgh Supecomputing Center, 300 South Craig Street, Pittsburgh, PA 15213

Registration Deadline: May 31, 2008

A workshop hosted by The National Resource for Biomedical Supercomputing at the Pittsburgh Supercomputing Center.

This workshop will cover theory and practice for the design and simulation of models focused on diffusion-reaction systems such as neurotransmission, signaling cascades, and other forms of biochemical networks (e.g., Coggan et al., 2005, Science 309:446-451; He et al., 2006, Nature 444:102-105). Current versions of the MCell/DReAMM simulation environment (www.mcell.psc.edu and www.mcell.cnl.salk.edu) will be introduced, including new Monte Carlo methods for 3-D simulation of reactions in solution and on arbitrarily shaped biological surfaces, as well as new tools for model design and visualization. Models created from both anatomical reconstruction tools and computer-aided design tools will be covered. Based on feedback from a similar highly successful workshop in June 2006, this workshop has been extended to five full days, and attendees will be strongly encouraged to bring ideas/data for their own simulation projects. The daily schedule will include theoretical and practical lectures, instructor-guided hands-on tutorials, and opportunities for one-on-one interaction with the instructors on individual project development. The primary instructors will be Joel Stiles (National Resource for Biomedical Supercomputing) and Thomas Bartol (Computational Neurobiology Laboratory, The Salk Institute), the original developers of MCell and DReAMM.

Application

Workshop content will be targeted to graduate student, postdoctoral, and faculty-level attendees. Those interested are encouraged to apply as soon as possible because space is limited. Openings will be assigned based on evaluation of information provided by applicants. To apply online, please use the link below. For more information, please contact Christal Banks at cbanks@psc.edu.

Financial Information

This workshop is funded by grants from the NIH National Center for Research Resources. These grants provide tuition and hotel costs, supercomputing time, and workshop materials for US academic participants. ALL participants are responsible for paying their own travel expenses. Complimentary continental breakfasts and lunches will be provided the days of the workshop.

A few positions may be available for US government employees and corporate and industrial researchers. These participants are responsible for their own hotel accommodations, and tuition costs are as follows:

  • a) Tuition for US government employees is $350 in advance to cover the workshop materials and supercomputing time. Contract government employees will be considered an academic participant and therefore their tuition costs will be waived if they submit a letter from their department head. Letters can be sent to the NRBSC contacts.
  • b) Tuition for corporate and industrial participants is $975 in advance to cover the workshop materials and supercomputing time.

The National Resource for Biomedical Supercomputing (an NIH NCRR Resource Center) pursues leading edge research and education in high performance computing and the life sciences, with focus areas in microphysiology, visualization and analysis of massive volumetric datasets, and computational structural biology. For additional information see http://www.nrbsc.org.

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NRBSC Gateways

Microphysiology Gateway image.

Volumetric Data and Viz Gateway Analysis.

Quantum Mechanics/Molecular Mechanics Simulation Gateway.


NRBSC projects are made possible by these sponsors:

NIH logo. Pittsburgh Supercomputing Center logo. NCRR logo.